Functional effects of N‐acetyltransferase 1 (NAT1*10) polymorphisms
نویسندگان
چکیده
منابع مشابه
Approximation to the distribution of fitness effects across 1 functional categories in human segregating polymorphisms
6 Quantifying the proportion of polymorphic mutations that are deleterious or neutral is of fundamental 7 importance to our understanding of evolution, disease genetics and the maintenance of variation genome8 wide. Here, we develop an approximation to the distribution of fitness effects (DFE) of segregating single9 nucleotide mutations in humans. Unlike previous methods, we do not assume that ...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2009
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.23.1_supplement.lb394